{"id":1892,"date":"2021-01-20T17:31:34","date_gmt":"2021-01-20T16:31:34","guid":{"rendered":"https:\/\/wordpress-test.app.u-pariscite.fr\/sdv\/?page_id=1892"},"modified":"2021-01-20T17:31:34","modified_gmt":"2021-01-20T16:31:34","slug":"immuno-pathologie-et-immuno-modulations-des-maladies-cardio-vasculaires","status":"publish","type":"page","link":"https:\/\/wordpress-test.app.u-pariscite.fr\/sdv\/immuno-pathologie-et-immuno-modulations-des-maladies-cardio-vasculaires\/","title":{"rendered":"Immuno-pathologie et immuno-modulations des maladies cardio-vasculaires"},"content":{"rendered":"<p>[et_pb_section bb_built=\u00a0\u00bb1&Prime;][et_pb_row][et_pb_column type=\u00a0\u00bb4_4&Prime;][et_pb_post_title _builder_version=\u00a0\u00bb3.22.1&Prime; meta=\u00a0\u00bboff\u00a0\u00bb featured_image=\u00a0\u00bboff\u00a0\u00bb text_shadow_horizontal_length=\u00a0\u00bbtext_shadow_style,%91object Object%93&Prime; text_shadow_vertical_length=\u00a0\u00bbtext_shadow_style,%91object Object%93&Prime; 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\/][\/et_pb_column][\/et_pb_row][et_pb_row][et_pb_column type=\u00a0\u00bb4_4&Prime;][et_pb_text _builder_version=\u00a0\u00bb3.22.1&Prime; text_text_shadow_horizontal_length=\u00a0\u00bbtext_text_shadow_style,%91object Object%93&Prime; text_text_shadow_vertical_length=\u00a0\u00bbtext_text_shadow_style,%91object Object%93&Prime; text_text_shadow_blur_strength=\u00a0\u00bbtext_text_shadow_style,%91object Object%93&Prime; link_text_shadow_horizontal_length=\u00a0\u00bblink_text_shadow_style,%91object Object%93&Prime; link_text_shadow_vertical_length=\u00a0\u00bblink_text_shadow_style,%91object Object%93&Prime; link_text_shadow_blur_strength=\u00a0\u00bblink_text_shadow_style,%91object Object%93&Prime; ul_text_shadow_horizontal_length=\u00a0\u00bbul_text_shadow_style,%91object Object%93&Prime; ul_text_shadow_vertical_length=\u00a0\u00bbul_text_shadow_style,%91object Object%93&Prime; ul_text_shadow_blur_strength=\u00a0\u00bbul_text_shadow_style,%91object Object%93&Prime; ol_text_shadow_horizontal_length=\u00a0\u00bbol_text_shadow_style,%91object Object%93&Prime; ol_text_shadow_vertical_length=\u00a0\u00bbol_text_shadow_style,%91object Object%93&Prime; ol_text_shadow_blur_strength=\u00a0\u00bbol_text_shadow_style,%91object Object%93&Prime; quote_text_shadow_horizontal_length=\u00a0\u00bbquote_text_shadow_style,%91object Object%93&Prime; quote_text_shadow_vertical_length=\u00a0\u00bbquote_text_shadow_style,%91object Object%93&Prime; quote_text_shadow_blur_strength=\u00a0\u00bbquote_text_shadow_style,%91object Object%93&Prime; header_text_shadow_horizontal_length=\u00a0\u00bbheader_text_shadow_style,%91object Object%93&Prime; header_text_shadow_vertical_length=\u00a0\u00bbheader_text_shadow_style,%91object Object%93&Prime; header_text_shadow_blur_strength=\u00a0\u00bbheader_text_shadow_style,%91object Object%93&Prime; header_2_text_shadow_horizontal_length=\u00a0\u00bbheader_2_text_shadow_style,%91object Object%93&Prime; header_2_text_shadow_vertical_length=\u00a0\u00bbheader_2_text_shadow_style,%91object Object%93&Prime; header_2_text_shadow_blur_strength=\u00a0\u00bbheader_2_text_shadow_style,%91object Object%93&Prime; header_3_text_shadow_horizontal_length=\u00a0\u00bbheader_3_text_shadow_style,%91object Object%93&Prime; header_3_text_shadow_vertical_length=\u00a0\u00bbheader_3_text_shadow_style,%91object Object%93&Prime; header_3_text_shadow_blur_strength=\u00a0\u00bbheader_3_text_shadow_style,%91object Object%93&Prime; header_4_text_shadow_horizontal_length=\u00a0\u00bbheader_4_text_shadow_style,%91object Object%93&Prime; header_4_text_shadow_vertical_length=\u00a0\u00bbheader_4_text_shadow_style,%91object Object%93&Prime; header_4_text_shadow_blur_strength=\u00a0\u00bbheader_4_text_shadow_style,%91object Object%93&Prime; header_5_text_shadow_horizontal_length=\u00a0\u00bbheader_5_text_shadow_style,%91object Object%93&Prime; header_5_text_shadow_vertical_length=\u00a0\u00bbheader_5_text_shadow_style,%91object Object%93&Prime; header_5_text_shadow_blur_strength=\u00a0\u00bbheader_5_text_shadow_style,%91object Object%93&Prime; header_6_text_shadow_horizontal_length=\u00a0\u00bbheader_6_text_shadow_style,%91object Object%93&Prime; header_6_text_shadow_vertical_length=\u00a0\u00bbheader_6_text_shadow_style,%91object Object%93&Prime; header_6_text_shadow_blur_strength=\u00a0\u00bbheader_6_text_shadow_style,%91object Object%93&Prime; z_index_tablet=\u00a0\u00bb500&Prime;]<\/p>\n<h3>\u00a0<\/h3>\n<h3><strong>This team is co-directed by Giuseppina CALIGURI and Antonino NICOLETTI, and is part of the UMRS 1148 unit<\/strong><\/h3>\n<p>\u00a0<\/p>\n<h4>PRESENTATION<\/h4>\n<p>The research in this team is devoted to study the multiple mechanisms through which the immune system<\/p>\n<p>interacts with diseased vessels and we design\u00a0new vascular-protective immunointervention\u00a0strategies.\u00a0Our research program relies\u00a0on specific skills and tools: experimental animal models, tissue biobank, (immuno-)histology, and up-to-date flow cytometry core.<\/p>\n<p>\u00a0<\/p>\n<p><strong>In the recent years, we have:<\/strong><\/p>\n<ul>\n<li>Identified the\u00a0CD31 as a molecule of pacification of the blood-vessel interface and have brought\u00a0the proof of concept of its therapeutic potential;<\/li>\n<li>Deciphered\u00a0local immune responses around atherothrombotic vessels and defined novel pathogenic immune pathways in the advanced stages of atherothrombotic disease;<\/li>\n<li>Targeted the neutrophils and their molecular effectors in\u00a0stroke.<\/li>\n<\/ul>\n<p><strong>Our\u00a0current major research focuses are:\u00a0<\/strong><\/p>\n<ul>\n<li>To suppress adverse vascular effects of reperfusion in brain, heart, intestine, and lungs;<\/li>\n<li>To evaluate new immune-related pathways and immunointervention strategies;<\/li>\n<li>To investigate the causal link between atherothrombosis and periodontal diseases;<\/li>\n<li>To evaluate the role of CD31 in transplantation;<\/li>\n<li>To discover new cellular and molecular pathways leading to aortic valve calcification.<\/li>\n<\/ul>\n<p>\u00a0<\/p>\n<p><a href=\"https:\/\/lvts.fr\/teams\/team-1\/\">Link to the web site<\/a><\/p>\n<p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section]<\/p>\n","protected":false},"excerpt":{"rendered":"<div class=\"et_pb_row et_pb_row_0 et_pb_row_empty\"><\/div>\n<div class=\"et_pb_row et_pb_row_1 et_pb_row_empty\"><\/div>\n<div class=\"et_pb_row et_pb_row_2 et_pb_row_empty\"><\/div>\n<p> \u00a0This team is co-directed by Giuseppina CALIGURI and Antonino NICOLETTI, and is part of the UMRS 1148 unit\u00a0PRESENTATIONThe research in this team is devoted to study the multiple mechanisms through which the immune systeminteracts with diseased vessels and we design\u00a0new vascular-protective immunointervention\u00a0strategies.\u00a0Our research program relies\u00a0on specific skills and tools: experimental animal models, tissue biobank,&hellip; <a class=\"continue\" href=\"https:\/\/wordpress-test.app.u-pariscite.fr\/sdv\/immuno-pathologie-et-immuno-modulations-des-maladies-cardio-vasculaires\/\">Lire la suite<span> Immuno-pathologie et immuno-modulations des maladies cardio-vasculaires<\/span><\/a><\/p>\n","protected":false},"author":69,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"","_et_gb_content_width":"","footnotes":""},"class_list":["post-1892","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/wordpress-test.app.u-pariscite.fr\/sdv\/wp-json\/wp\/v2\/pages\/1892","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/wordpress-test.app.u-pariscite.fr\/sdv\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/wordpress-test.app.u-pariscite.fr\/sdv\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/wordpress-test.app.u-pariscite.fr\/sdv\/wp-json\/wp\/v2\/users\/69"}],"replies":[{"embeddable":true,"href":"https:\/\/wordpress-test.app.u-pariscite.fr\/sdv\/wp-json\/wp\/v2\/comments?post=1892"}],"version-history":[{"count":2,"href":"https:\/\/wordpress-test.app.u-pariscite.fr\/sdv\/wp-json\/wp\/v2\/pages\/1892\/revisions"}],"predecessor-version":[{"id":1894,"href":"https:\/\/wordpress-test.app.u-pariscite.fr\/sdv\/wp-json\/wp\/v2\/pages\/1892\/revisions\/1894"}],"wp:attachment":[{"href":"https:\/\/wordpress-test.app.u-pariscite.fr\/sdv\/wp-json\/wp\/v2\/media?parent=1892"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}