{"id":1618,"date":"2021-01-09T09:23:41","date_gmt":"2021-01-09T08:23:41","guid":{"rendered":"https:\/\/wordpress-test.app.u-pariscite.fr\/sdv\/?page_id=1618"},"modified":"2021-01-10T17:31:24","modified_gmt":"2021-01-10T16:31:24","slug":"molecular-genetics-of-rna-viruses","status":"publish","type":"page","link":"https:\/\/wordpress-test.app.u-pariscite.fr\/sdv\/molecular-genetics-of-rna-viruses\/","title":{"rendered":"Molecular Genetics of RNA viruses"},"content":{"rendered":"

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GMVR<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n
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Tutelles\u00a0><\/div>\n
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Institut Pasteur<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n
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UFR de rattachement\u00a0><\/div>\n
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Sciences du Vivant<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n
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Label unit\u00e9\u00a0><\/div>\n
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UMR 3569<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n
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Pr\u00e9sentation<\/h3>\n
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\u00b7\u00a0<\/strong>Objectives<\/strong><\/u>\u00a0:<\/p>\n

Studies on influenza viruses and other respiratory viruses are mainly focused on<\/u>\u00a0:<\/p>\n

\u25ba Epidemiology\u00a0<\/em>and\u00a0evolution\u00a0<\/em>of influenza viruses in close link with the National Influenza Center (Northern-France) and WHO reference laboratory for H5 viruses focusing on the the diversity of the viral populations and their functional impact on pathogenicity and adaptation to a new host.<\/p>\n

\u25baInfluenza virus \u2013 host interactions\u00a0<\/em>specifically on interactions between viral ribonucleoproteins and the cellular microenvironment and analysis of determinants of pathogenicity on the neuraminidase of avian influenza viruses.<\/p>\n

\u25baAntiviral inhibitors of influenza virus multiplication<\/em>, evaluating the impact of virus genetic variations on the susceptibility to antiviral inhibitors and viral fitness.<\/p>\n

\u25baImmune responses and vaccines<\/em>\u00a0to analyze the humoral responses to anti-influenza vaccination.<\/p>\n

Studies of hepatitis C virus (HCV) and related simian GB virus B (GBV-B) focus on<\/u>\u00a0:<\/p>\n

\u25baVirus cell entry, particle assembly and host range and on Virus\/host interactions\u00a0 small primate model.<\/p>\n

The unit is : the CNRS National Reference Center for influenza viruses, WHO National Influenza Center (Northern-France) and WHO reference laboratory for H5 and SARS.\u00a0<\/p>\n

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\u00b7\u00a0<\/strong>Methods<\/strong><\/u>\u00a0:<\/p>\n

Molecular, biochemical and cellular in vitro approaches, and in vivo studies. The laboratory has access to BSL2+ and BSL3+ facilities and to the platforms of the Institut Pasteur (sequencing, imaging, A2 and A3 animal facilities, etc..).<\/p>\n<\/div>\n<\/div>\n<\/div>\n

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Equipes de recherche<\/h3>\n
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Responsable de Structure : Sylvie Van Der Werf
Vincent Enouf : Directeur(trice) Adjoint(e) de Centre National de R\u00e9f\u00e9rence<\/p>\n

Mathilde Ben Assaya : Technicienne
Andreea Alexandru
St\u00e9phane Leandri
Camille Berthault
Marion Declercq : Etudiante en th\u00e8se
Melanie Dos Santos
Marie Lazzerini
Brigitte Blumen
Malika Hocine
Camille Roquin
Sylvie Behillil
Nadia Naffakh : Cheffe de Groupe
Florian Andrieux
Cyril Barbezange : Chercheur Permanent
Caroline Demeret
Guillaume Fournier : Post-doctorant
Sandie Munier
Bernadette Crescenzo : Ing\u00e9nieure de Recherche
Julie Magnus : Ing\u00e9nieure de Recherche
Lisette Cohen
Matthieu Fritz : Etudiant en th\u00e8se
Patricia Cassonnet : Ing\u00e9nieure de Recherche
St\u00e9phanie Aicher : Etudiante en th\u00e8se
Elise Biquand : Etudiante en th\u00e8se
C\u00e9dric Diot : Etudiant en th\u00e8se
Yves Jacob : Chef de Groupe
Annette Martin : Cheffe de Groupe
Isabelle Poste : Personnel Administratif<\/p>\n<\/div>\n<\/div>\n<\/div>\n

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AUTRES CONTACTS<\/h3>\n
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Institut Pasteur<\/p>\n

25, rue du Dr Roux<\/p>\n

75724 PARIS CEDEX 15<\/p>\n<\/div>\n<\/div>\n<\/div>\n

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Lien(s) web\u00a0><\/div>\n
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https:\/\/research.pasteur.fr\/fr\/team\/molecular-genetics-of-rna-viruses<\/a><\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n
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Localisation<\/h3>\n
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25, rue du Dr Roux<\/div>\n

75015<\/span>\u00a0PARIS<\/span><\/div>\n<\/div>\n

France<\/div>\n<\/div>\n<\/div>\n<\/div>\n

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GMVR \u00a0 Tutelles\u00a0> Institut Pasteur \u00a0 UFR de rattachement\u00a0> Sciences du Vivant \u00a0 \u00a0 Label unit\u00e9\u00a0> UMR 3569 \u00a0 Pr\u00e9sentation \u00b7\u00a0Objectives\u00a0: Studies on influenza viruses and other respiratory viruses are mainly focused on\u00a0: \u25ba Epidemiology\u00a0and\u00a0evolution\u00a0of influenza viruses in close link with the National Influenza Center (Northern-France) and WHO reference laboratory for H5 viruses focusing… Lire la suite Molecular Genetics of RNA viruses<\/span><\/a><\/p>\n","protected":false},"author":69,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"","_et_gb_content_width":"","footnotes":""},"class_list":["post-1618","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/wordpress-test.app.u-pariscite.fr\/sdv\/wp-json\/wp\/v2\/pages\/1618","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/wordpress-test.app.u-pariscite.fr\/sdv\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/wordpress-test.app.u-pariscite.fr\/sdv\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/wordpress-test.app.u-pariscite.fr\/sdv\/wp-json\/wp\/v2\/users\/69"}],"replies":[{"embeddable":true,"href":"https:\/\/wordpress-test.app.u-pariscite.fr\/sdv\/wp-json\/wp\/v2\/comments?post=1618"}],"version-history":[{"count":3,"href":"https:\/\/wordpress-test.app.u-pariscite.fr\/sdv\/wp-json\/wp\/v2\/pages\/1618\/revisions"}],"predecessor-version":[{"id":1672,"href":"https:\/\/wordpress-test.app.u-pariscite.fr\/sdv\/wp-json\/wp\/v2\/pages\/1618\/revisions\/1672"}],"wp:attachment":[{"href":"https:\/\/wordpress-test.app.u-pariscite.fr\/sdv\/wp-json\/wp\/v2\/media?parent=1618"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}