{"id":1585,"date":"2021-01-09T08:45:19","date_gmt":"2021-01-09T07:45:19","guid":{"rendered":"https:\/\/wordpress-test.app.u-pariscite.fr\/sdv\/?page_id=1585"},"modified":"2021-01-21T09:55:50","modified_gmt":"2021-01-21T08:55:50","slug":"stabilite-genetique-cellules-souches-et-radiations-2","status":"publish","type":"page","link":"https:\/\/wordpress-test.app.u-pariscite.fr\/sdv\/stabilite-genetique-cellules-souches-et-radiations-2\/","title":{"rendered":"Stabilit\u00e9 g\u00e9n\u00e9tique, cellules souches et radiations"},"content":{"rendered":"<p>[et_pb_section bb_built=\u00a0\u00bb1&Prime; next_background_color=\u00a0\u00bb#000000&Prime; inner_width=\u00a0\u00bbauto\u00a0\u00bb inner_max_width=\u00a0\u00bbnone\u00a0\u00bb][et_pb_row][et_pb_column type=\u00a0\u00bb4_4&Prime;][et_pb_post_title _builder_version=\u00a0\u00bb3.22.1&Prime; meta=\u00a0\u00bboff\u00a0\u00bb featured_image=\u00a0\u00bboff\u00a0\u00bb text_shadow_horizontal_length=\u00a0\u00bbtext_shadow_style,%91object Object%93&Prime; 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header_5_text_shadow_blur_strength=\u00a0\u00bbheader_5_text_shadow_style,%91object Object%93&Prime; header_6_text_shadow_horizontal_length=\u00a0\u00bbheader_6_text_shadow_style,%91object Object%93&Prime; header_6_text_shadow_vertical_length=\u00a0\u00bbheader_6_text_shadow_style,%91object Object%93&Prime; header_6_text_shadow_blur_strength=\u00a0\u00bbheader_6_text_shadow_style,%91object Object%93&Prime; z_index_tablet=\u00a0\u00bb500&Prime;]<\/p>\n<p><strong>Sigle<\/strong>\u00a0: SGCSR<\/p>\n<p><strong>Tutelles<\/strong>\u00a0: \u00a0Universit\u00e9 Paris Cit\u00e9, Universit\u00e9 Paris-Saclay, Inserm, CEA<\/p>\n<p><strong>UFR de rattachement<\/strong>\u00a0: Sciences du Vivant<\/p>\n<p><strong>Label unit\u00e9<\/strong>\u00a0: UMRE008-U1274<\/p>\n<p>\u00a0<\/p>\n<p><strong>Directeur :<\/strong> Fran\u00e7ois Boussin (<a href=\"mailto:francois.boussin@cea.fr\">francois.boussin@cea.fr<\/a>)\u00a0\u00a0<\/p>\n<p><strong>Directrice adjointe\u00a0: \u00a0<\/strong>Fran\u00e7oise Pflumio<strong> (<\/strong><a href=\"mailto:francoise.pflumio@cea.fr)\">francoise.pflumio@cea.fr)<\/a><\/p>\n<p><strong>\u00a0<\/strong><\/p>\n<h3><strong>Pr\u00e9sentation<\/strong>\u00a0:<\/h3>\n<p>L&rsquo;Unit\u00e9 Mixte de Recherche \u00ab\u00a0Stabilit\u00e9 G\u00e9n\u00e9tique, Cellules Souches et Radiations\u00a0\u00bb (SGCSR) consacre ses recherches aux m\u00e9canismes mol\u00e9culaires assurant la r\u00e9paration des dommages de l&rsquo;ADN et la stabilit\u00e9 du g\u00e9nome, ainsi qu\u2019aux cellules souches normales et canc\u00e9reuses (germinales, h\u00e9matopo\u00ef\u00e9tiques et neurales). La combinaison de ces deux th\u00e9matiques permet aux \u00e9quipes de l\u2019UMR de d\u00e9velopper une recherche originale sur la caract\u00e9risation des r\u00e9ponses cellulaires et tissulaires aux stress g\u00e9notoxiques notamment li\u00e9s \u00e0 l\u2019exposition aux radiations ionisantes. Pour cela, ils font appel \u00e0 diff\u00e9rents syst\u00e8mes mod\u00e8les (<em>Saccharomyces cerevisiae<\/em>, <em>Helicobacter pilori<\/em>) et mod\u00e8les pr\u00e9cliniques (souris). L&rsquo;objectif g\u00e9n\u00e9ral est de permettre une meilleure compr\u00e9hension du d\u00e9veloppement de diff\u00e9rentes pathologies canc\u00e9reuses et non-canc\u00e9reuses, afin de proposer de nouvelles strat\u00e9gies pr\u00e9ventives et\/ou\u00a0th\u00e9rapeutiques sp\u00e9cifiques.<\/p>\n<p>\u00a0<\/p>\n<h3><strong>Listes des Publications\u00a0:<\/strong><\/h3>\n<p>\u00a0<a href=\"https:\/\/www-cea-fr.admsite.extra.cea.fr\/drf\/ifrancoisjacob\/Pages\/Departements\/IRCM\/Productions-scientifiques\/Publications-IRCM.aspx\">https:\/\/www-cea-fr.admsite.extra.cea.fr\/drf\/ifrancoisjacob\/Pages\/Departements\/IRCM\/Productions-scientifiques\/Publications-IRCM.aspx<\/a><\/p>\n<p>\u00a0<\/p>\n<h3><strong>Equipes de recherche\u00a0:<\/strong><\/h3>\n<ul>\n<li>R\u00e9paration de l\u2019ADN et Stabilit\u00e9 des Chromosomes &#8211; Responsable : St\u00e9phane Marcand (<a href=\"mailto:stephane.marcand@cea.fr\">marcand@cea.fr<\/a>)<\/li>\n<li>Niche et Cancer dans l\u2019H\u00e9matopo\u00ef\u00e8se &#8211; Responsable : Fran\u00e7oise Pflumio (<a href=\"mailto:francoise.pflumio@cea.fr\">pflumio@cea.fr<\/a>)<\/li>\n<li>Neurogen\u00e8se, R\u00e9paration et Cancer \u2013 Responsable : Fran\u00e7ois Boussin (<a href=\"mailto:francois.boussin@cea.fr\">boussin@cea.fr<\/a>)<\/li>\n<li>Cancer et microenvironnement \u2013 Responsable : Claire Magnon (<a href=\"mailto:claire.magnon@cea.fr\">magnon@cea.fr<\/a>)<\/li>\n<li>Diff\u00e9renciation des Cellules Germinales \u2013 Responsable : Gabriel Livera (<a href=\"mailto:gabriel.livera@cea.fr\">livera@cea.fr<\/a>)<\/li>\n<li>Recherche sur l\u2019Instabilit\u00e9 G\u00e9n\u00e9tique \u2013 Responsable : Juan-Pablo Radicella (<a href=\"mailto:pablo.Radicella@cea.fr\">Radicella@cea.fr<\/a>)<\/li>\n<\/ul>\n<p><strong>\u00a0<\/strong><\/p>\n<h3><strong>Equipements\u00a0:<\/strong><\/h3>\n<p>Plateforme d\u2019irradiation\u00a0: <a href=\"mailto:veronique.menard@cea.fr\">veronique.menard@cea.fr<\/a><\/p>\n<p>Plateforme de microscopie\u00a0: <a href=\"mailto:lamya.irbah@cea.fr\">lamya.irbah@cea.fr<\/a><\/p>\n<p>Plateforme de cytom\u00e9trie\u00a0: <a href=\"mailto:jan.baijer@cea.fr\">jan.baijer@cea.fr<\/a><\/p>\n<p>Plateforme d\u2019ing\u00e9nierie g\u00e9n\u00e9tique (CIGEx)\u00a0: <a href=\"mailto:didier.busso@cea.fr\">didier.busso@cea.fr<\/a><\/p>\n<p>Plateforme d\u2019exp\u00e9rimentation animale\u00a0: <a href=\"mailto:vilma.barroca@cea.fr\">vilma.barroca@cea.fr<\/a><\/p>\n<p>Animalerie\u00a0: <a href=\"mailto:sylvia.vincent-naulleau@cea.fr\">sylvia.vincent-naulleau@cea.fr<\/a><\/p>\n<p>\u00a0<\/p>\n<h3><strong>Autres contacts\u00a0: <\/strong><\/h3>\n<p><u>Secr\u00e9tariat<\/u>\u00a0: Aur\u00e9lie Gouret &amp; Arielle Leliard (<a href=\"mailto:secretariat-u1274@cea.fr\">secretariat-u1274@cea.fr<\/a>)<\/p>\n<p>Adresse\u00a0:<\/p>\n<p>UMR SGCSR, iRCM\/IBFJ<\/p>\n<p>CEA<\/p>\n<p>B\u00e2timent 05<\/p>\n<p>18 route du Panorama<\/p>\n<p>92260 Fontenay-aux-Roses<\/p>\n<p>\u00a0<\/p>\n<p><a href=\"https:\/\/www.cea.fr\/drf\/ifrancoisjacob\/Pages\/Departements\/IRCM\/UMR-SGCSR.aspx\"><strong>Suivre ce lien vers le site web de l\u2019UMR\u00a0<\/strong><\/a><\/p>\n<p>\u00a0<\/p>\n<p>\u00a0<\/p>\n<p>\u00a0<\/p>\n<p>\u00a0<\/p>\n<p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row][et_pb_column type=\u00a0\u00bb1_2&Prime;][\/et_pb_column][et_pb_column type=\u00a0\u00bb1_2&Prime;][\/et_pb_column][\/et_pb_row][\/et_pb_section]<\/p>\n","protected":false},"excerpt":{"rendered":"<div class=\"et_pb_row et_pb_row_0 et_pb_row_empty\"><\/div>\n<div class=\"et_pb_row et_pb_row_1 et_pb_row_empty\"><\/div>\n<div class=\"et_pb_row et_pb_row_2 et_pb_row_empty\"><\/div>\n<div class=\"et_pb_row et_pb_row_3 et_pb_row_empty\"><\/div>\n<p> Sigle\u00a0: SGCSRTutelles\u00a0: \u00a0Universit\u00e9 Paris Cit\u00e9, Universit\u00e9 Paris-Saclay, Inserm, CEAUFR de rattachement\u00a0: Sciences du VivantLabel unit\u00e9\u00a0: UMRE008-U1274\u00a0Directeur : Fran\u00e7ois Boussin (francois.boussin@cea.fr)\u00a0\u00a0Directrice adjointe\u00a0: \u00a0Fran\u00e7oise Pflumio (francoise.pflumio@cea.fr)\u00a0Pr\u00e9sentation\u00a0:L&rsquo;Unit\u00e9 Mixte de Recherche \u00ab\u00a0Stabilit\u00e9 G\u00e9n\u00e9tique, Cellules Souches et Radiations\u00a0\u00bb (SGCSR) consacre ses recherches aux m\u00e9canismes mol\u00e9culaires assurant la r\u00e9paration des dommages de l&rsquo;ADN et la stabilit\u00e9 du g\u00e9nome, ainsi qu\u2019aux&hellip; <a class=\"continue\" href=\"https:\/\/wordpress-test.app.u-pariscite.fr\/sdv\/stabilite-genetique-cellules-souches-et-radiations-2\/\">Lire la suite<span> Stabilit\u00e9 g\u00e9n\u00e9tique, cellules souches et radiations<\/span><\/a><\/p>\n","protected":false},"author":69,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"","_et_gb_content_width":"","footnotes":""},"class_list":["post-1585","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/wordpress-test.app.u-pariscite.fr\/sdv\/wp-json\/wp\/v2\/pages\/1585","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/wordpress-test.app.u-pariscite.fr\/sdv\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/wordpress-test.app.u-pariscite.fr\/sdv\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/wordpress-test.app.u-pariscite.fr\/sdv\/wp-json\/wp\/v2\/users\/69"}],"replies":[{"embeddable":true,"href":"https:\/\/wordpress-test.app.u-pariscite.fr\/sdv\/wp-json\/wp\/v2\/comments?post=1585"}],"version-history":[{"count":8,"href":"https:\/\/wordpress-test.app.u-pariscite.fr\/sdv\/wp-json\/wp\/v2\/pages\/1585\/revisions"}],"predecessor-version":[{"id":1901,"href":"https:\/\/wordpress-test.app.u-pariscite.fr\/sdv\/wp-json\/wp\/v2\/pages\/1585\/revisions\/1901"}],"wp:attachment":[{"href":"https:\/\/wordpress-test.app.u-pariscite.fr\/sdv\/wp-json\/wp\/v2\/media?parent=1585"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}