{"id":1582,"date":"2021-01-09T08:42:42","date_gmt":"2021-01-09T07:42:42","guid":{"rendered":"https:\/\/wordpress-test.app.u-pariscite.fr\/sdv\/?page_id=1582"},"modified":"2021-01-21T10:07:42","modified_gmt":"2021-01-21T09:07:42","slug":"stem-cells-and-radiations","status":"publish","type":"page","link":"https:\/\/wordpress-test.app.u-pariscite.fr\/sdv\/stem-cells-and-radiations\/","title":{"rendered":"Stem Cells and Radiations"},"content":{"rendered":"

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Sigle<\/strong>\u00a0: SGCSR<\/p>\n

Tutelles<\/strong>\u00a0: \u00a0Universit\u00e9 Paris Cit\u00e9, Universit\u00e9 Paris-Saclay, Inserm, CEA<\/p>\n

UFR de rattachement<\/strong>\u00a0: Sciences du Vivant<\/p>\n

Label unit\u00e9<\/strong>\u00a0: UMRE008-U1274<\/p>\n

\u00a0<\/p>\n

Directeur :<\/strong> Fran\u00e7ois Boussin (francois.boussin@cea.fr<\/a>)\u00a0\u00a0<\/p>\n

Directrice adjointe\u00a0:\u00a0 <\/strong>Fran\u00e7oise Pflumio (<\/strong>francoise.pflumio@cea.fr)<\/a><\/p>\n

\u00a0<\/h4>\n

Pr\u00e9sentation<\/strong>\u00a0:<\/h4>\n

UMR Genetic Stability, Stem Cells and Radiation (SGCSR) studies the molecular mechanisms ensuring DNA repair and genome stability and normal and cancer stem cell biology (germinal, hematopoietic and neural stem cells). Combination of these research themes gives to the UMR\u2019s teams unique opportunities to develop original research topics aiming to characterize the cellular and tissue responses to genotoxic stress such as ionizing radiation. To this end, they develop several model systems (Saccharomyces cerevisiae, Helicobacter pilori<\/em>) and preclinical models (mice). The goal is to provide a better understanding of the development of various cancer and non-cancer pathologies in order to propose new specific preventive and\/or therapeutic strategies.<\/p>\n

\u00a0<\/p>\n

Publications\u00a0:<\/strong><\/h4>\n

\u00a0https:\/\/www-cea-fr.admsite.extra.cea.fr\/drf\/ifrancoisjacob\/Pages\/Departements\/IRCM\/Productions-scientifiques\/Publications-IRCM.aspx<\/a><\/p>\n

\u00a0<\/p>\n

Research teams:<\/strong><\/h4>\n