{"id":1548,"date":"2021-01-08T17:20:21","date_gmt":"2021-01-08T16:20:21","guid":{"rendered":"https:\/\/wordpress-test.app.u-pariscite.fr\/sdv\/?page_id=1548"},"modified":"2021-01-09T15:41:33","modified_gmt":"2021-01-09T14:41:33","slug":"institut-jacques-monod-english-version","status":"publish","type":"page","link":"https:\/\/wordpress-test.app.u-pariscite.fr\/sdv\/institut-jacques-monod-english-version\/","title":{"rendered":"Institut Jacques Monod (english version)"},"content":{"rendered":"

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Tutelles ><\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n
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Universit\u00e9 Paris Diderot<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n
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UFR de rattachement\u00a0><\/div>\n
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SCIENCES DU VIVANT<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n
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Label unit\u00e9 ><\/div>\n<\/div>\n
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UMR 7592<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n
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Partenaires\u00a0><\/div>\n
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CNRS<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n
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Pr\u00e9sentation<\/h3>\n
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The overall goal of the research groups is to understand the fundamental processes contributing to the structure, dynamics and functions of eukaryotic cells. Different cellular components are studied (nuclei, transport vesicles, mitochondria, cytoskeleton etc), their assembly, regulation, signalling pathways and their roles in determining cell shape, motility, proliferation, tissue organization and development, in both normal and pathological conditions.<\/p>\n

Some groups study the genetic, cellular and molecular mechanisms that underlie animal development, in particular those that control the formation of the nervous system. They also study the evolution of developmental processes.<\/p>\n

Other teams are interested in the regulation of DNA and protein metabolism. This includes fundamental processes of genome maintenance such as the control of DNA replication and damage repair; transcriptional regulation; nucleo-cytoplasmic trafficking and regulation of cellular trafficking by ubiquitylation; protein processing, folding and export.
In the\u00a0first transverse perspective<\/u>, several teams develop new theoretical and\/or practical approaches to gain a better understanding of the molecular and cellular bases of rare diseases (genetic diseases) and more common affections (cancer, diseases of reproduction, autoimmune diseases etc.).
Finally, in the\u00a0second transverse perspective<\/u>\u00a0some groups are actively engaged in research and development of novel methods and resources in mathematical modelling and biophysical analysis of biological objects and phenomena.<\/p>\n

Belongs to SdV sector :<\/p>\n

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  1. The basic elements of living organisms<\/li>\n
  2. The assembly of living organisms<\/li>\n
  3. The survival and defense of living organisms<\/li>\n<\/ol>\n<\/div>\n<\/div>\n<\/div>\n
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    Th\u00e8mes de recherche<\/h3>\n
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    THE IJM PURSUES BASIC RESEARCH WITHIN THREE MAJOR THEMES<\/strong>\u00a0:<\/h3>\n

    \u2666\u00a0Genome and chromosome dynamics<\/p>\n

    \u2666\u00a0Cellular dynamics and signalling<\/p>\n

    \u2666 Development and evolution<\/p>\n

    Furthermore\u00a0two transverse themes<\/u>\u00a0consist in :<\/p>\n

    a) Modelling, quantitative biology and biophysics
    b) Molecular and cellular pathologies.<\/p>\n

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    Methods\u00a0<\/strong>: In-vivo and in-vitro approaches in model systems such as : yeast, drosophila, zebra fish, mouse, rat. Genetics, cellular and molecular biology (transcriptomics, proteomics, flow cytometry, cellular imaging).<\/p>\n<\/div>\n<\/div>\n<\/div>\n

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    Equipes de recherche<\/h3>\n
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    TEAMS\u00a0<\/strong><\/u>:<\/p>\n

    -Equipe 1 : Juliette Azimzadeh (Polarit\u00e9 cellulaire dans le d\u00e9veloppement et l’\u00e9volution)<\/p>\n

    -Equipe 2 : Guillaume Balavoine\/Michel Vervoort (\u00c9volution et d\u00e9veloppement des m\u00e9tazoaires)<\/p>\n

    -Equipe 3 : Giuseppe Baldacci (Pathologies de la r\u00e9plication de l’ADN)<\/p>\n

    -Equipe 4 : Nicolas Borghi ( M\u00e9canotransduction : de la surface de la cellule \u00e0 son noyau)<\/p>\n

    -Equipe 5 : Jean-Michel Camadro (Mitochondries, m\u00e9taux et stress oxydatif)<\/p>\n

    -Equipe 6 : J\u00e9r\u00f4me Collignon (Sp\u00e9cification des destins cellulaires chez la souris)<\/p>\n

    -Equipe 7 : Val\u00e9rie Doye (Fonctions non-conventionnelles des pores nucl\u00e9aires)<\/p>\n

    -Equipe 8 : Sandra Duharcourt (R\u00e9gulation \u00e9pig\u00e9n\u00e9tique de l’organisation du g\u00e9nome)<\/p>\n

    -Equipe 9 : Julien Dumont (Division cellulaire et reproduction)<\/p>\n

    -Equipe 10 : Thierry Galli (Trafic membranaire normal et pathologique)<\/p>\n

    -Equipe 11 : Thierry Grange\/Eva-Maria Geigl (\u00c9pig\u00e9nome et pal\u00e9og\u00e9nome)<\/p>\n

    -Equipe 12 : Antoine Guichet ( Polarit\u00e9 et morphogen\u00e8se)<\/p>\n

    -Equipe 13 : Cathy Jackson\/Jean-Marc Verbavatz (Dynamique des membranes et trafic intracellulaire)<\/p>\n

    -Equipe 14 : Isabelle Jupin (Virologie mol\u00e9culaire)<\/p>\n

    -Equipe 15 : Roger Karess (Dynamique et r\u00e9gulation de la division cellulaire)<\/p>\n

    -Equipe 16 : Beno\u00eet Ladoux\/ Ren\u00e9-Marc M\u00e8ge (Adh\u00e9sion cellulaire et m\u00e9canique)<\/p>\n

    -Equipe 17 : S\u00e9bastien Leon (Trafic membranaire, ubiquitine et signalisation)<\/p>\n

    -Equipe 18 : Domenico Libri (M\u00e9tabolisme et fonction de l’ARN dans le noyau)<\/p>\n

    -Equipe 19 : Nicolas Minc (Organisation spatiale de la cellule)<\/p>\n

    -Equipe 20 : Virginie Orgogozo (\u00c9volution des drosophiles)<\/p>\n

    -Equipe 21 : Khashayar Pakdaman (Biologie computationnelle et biomath\u00e9matiques)<\/p>\n

    -Equipe 22 : Alessandra Pierani (G\u00e9n\u00e9tique et d\u00e9veloppement du cortex c\u00e9r\u00e9bral)<\/p>\n

    -Equipe 23 : Lionel Pintard (Cycle cellulaire et d\u00e9veloppement)<\/p>\n

    -Equipe 24 : Anne Plessis (D\u00e9veloppement, signalisation et trafic)<\/p>\n

    -Equipe 25 : Fran\u00e7oise Poirier (Morphogen\u00e8se, hom\u00e9ostasie et pathologies)<\/p>\n

    -Equipe 26 : Marie-No\u00eblle Prioleau (Domaines chromatiniens et r\u00e9plication)<\/p>\n

    -Equipe 27 : Vanessa Ribes (R\u00e9seaux transcriptionnels et diff\u00e9renciation neurale)<\/p>\n

    -Equipe 28 : Guillaume Romet-Lemonne (R\u00e9gulation de la dynamique d’assemblage de l’actine)<\/p>\n

    -Equipe 29 : Terence Strick (Nanomanipulation de biomol\u00e9cules)<\/p>\n

    -Equipe 30 : Reiner Veitia (Oncologie mol\u00e9culaire et pathologies ovariennes)<\/p>\n<\/div>\n<\/div>\n<\/div>\n

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    Lien(s) web\u00a0><\/div>\n
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    http:\/\/www.ijm.fr\/<\/a><\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n
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    Localisation<\/h3>\n
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    15 rue H\u00e9l\u00e8ne Brion<\/div>\n
    B\u00e2timent Buffon<\/span><\/div>\n

    75013<\/span>\u00a0PARIS<\/span><\/div>\n<\/div>\n

    France<\/div>\n<\/div>\n<\/div>\n<\/div>\n

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    \u00a0 Tutelles > Universit\u00e9 Paris Diderot \u00a0 UFR de rattachement\u00a0> SCIENCES DU VIVANT \u00a0 Label unit\u00e9 > UMR 7592 \u00a0 Partenaires\u00a0> CNRS \u00a0 Pr\u00e9sentation The overall goal of the research groups is to understand the fundamental processes contributing to the structure, dynamics and functions of eukaryotic cells. Different cellular components are studied (nuclei, transport… Lire la suite Institut Jacques Monod (english version)<\/span><\/a><\/p>\n","protected":false},"author":69,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"","_et_gb_content_width":"","footnotes":""},"class_list":["post-1548","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/wordpress-test.app.u-pariscite.fr\/sdv\/wp-json\/wp\/v2\/pages\/1548","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/wordpress-test.app.u-pariscite.fr\/sdv\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/wordpress-test.app.u-pariscite.fr\/sdv\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/wordpress-test.app.u-pariscite.fr\/sdv\/wp-json\/wp\/v2\/users\/69"}],"replies":[{"embeddable":true,"href":"https:\/\/wordpress-test.app.u-pariscite.fr\/sdv\/wp-json\/wp\/v2\/comments?post=1548"}],"version-history":[{"count":3,"href":"https:\/\/wordpress-test.app.u-pariscite.fr\/sdv\/wp-json\/wp\/v2\/pages\/1548\/revisions"}],"predecessor-version":[{"id":1647,"href":"https:\/\/wordpress-test.app.u-pariscite.fr\/sdv\/wp-json\/wp\/v2\/pages\/1548\/revisions\/1647"}],"wp:attachment":[{"href":"https:\/\/wordpress-test.app.u-pariscite.fr\/sdv\/wp-json\/wp\/v2\/media?parent=1548"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}