{"id":1583,"date":"2024-10-10T16:28:37","date_gmt":"2024-10-10T14:28:37","guid":{"rendered":"https:\/\/wordpress-test.app.u-pariscite.fr\/diip\/?p=1583"},"modified":"2024-10-21T17:03:48","modified_gmt":"2024-10-21T15:03:48","slug":"influence-of-blood-pressure-and-aqueous-humor-dynamics-on-the-response-to-glaucoma-medication-a-data-driven-computational-study","status":"publish","type":"post","link":"https:\/\/wordpress-test.app.u-pariscite.fr\/diip\/influence-of-blood-pressure-and-aqueous-humor-dynamics-on-the-response-to-glaucoma-medication-a-data-driven-computational-study\/","title":{"rendered":"Influence of blood pressure and aqueous humor dynamics on the response to glaucoma medication: a data-driven computational study"},"content":{"rendered":"<p>[et_pb_section fb_built=&#8221;1&#8243; _builder_version=&#8221;3.22&#8243;][et_pb_row _builder_version=&#8221;3.22&#8243; background_size=&#8221;initial&#8221; background_position=&#8221;top_left&#8221; background_repeat=&#8221;repeat&#8221;][et_pb_column type=&#8221;1_4&#8243; _builder_version=&#8221;3.0.47&#8243;][et_pb_text _builder_version=&#8221;3.22.1&#8243; background_color=&#8221;#072c72&#8243; border_color_all=&#8221;#3255c9&#8243; text_orientation=&#8221;right&#8221; background_layout=&#8221;dark&#8221; custom_padding=&#8221;20px|15px|15px|&#8221; z_index_tablet=&#8221;500&#8243;]<\/p>\n<p><em>2021<\/em><\/p>\n<p><em>Masters Projects<\/em><\/p>\n<p><span data-sheets-root=\"1\">@Mathematics and Statistics<\/span><\/p>\n<p>[\/et_pb_text][et_pb_text _builder_version=&#8221;3.22.1&#8243; text_orientation=&#8221;right&#8221; z_index_tablet=&#8221;500&#8243;]<\/p>\n<p>+Computer Science<\/p>\n<p>+Mathematics\/Statistics<\/p>\n<p>+Engineering<\/p>\n<p>+Medicine<\/p>\n<p>\u00a0<\/p>\n<p>#data-driven computational study<\/p>\n<p>#mathematical modeling<\/p>\n<p>#glaucoma<\/p>\n<p>#enhanced data set<\/p>\n<p>\u00a0<\/p>\n<p>[\/et_pb_text][\/et_pb_column][et_pb_column type=&#8221;3_4&#8243; _builder_version=&#8221;3.0.47&#8243;][et_pb_text _builder_version=&#8221;3.22.1&#8243; z_index_tablet=&#8221;500&#8243;]<\/p>\n<h3><strong>Project Summary<\/strong><\/h3>\n<p>Intraocular pressure (IOP) is the pressure created by the fluids within the eye. Elevated IOP is clinically referred to as ocular hypertension and it represents a major risk factor for irreversible vision loss, as in glaucoma. However, the establishment of optimal IOP levels for patients is still controversial. Another meaningful open question is related to what determines the efficacy of IOP-lowering medications. Motivated by this context, the intern will work on the construction and analysis of an enhanced data set, obtained by combining a clinical data set from the Indianapolis Glaucoma Progression Study and a novel physically-based simulated data set. The objective is to address the specific question of quantifying the impact of systemic factors (such as blood pressure) and local factors (such as production and drainage of aqueous humor) on the response to IOP-lowering medication in different conditions of clinical interest, thereby enabling more effective, personalised patient care.<\/p>\n<p>\u00a0<\/p>\n<h5><strong>Marcela Szopos<\/strong><\/h5>\n<p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row custom_margin=&#8221;120px||&#8221; _builder_version=&#8221;3.22.1&#8243; admin_label=&#8221;Row&#8221; locked=&#8221;off&#8221;][et_pb_column type=&#8221;4_4&#8243; _builder_version=&#8221;3.22.1&#8243;][et_pb_divider _builder_version=&#8221;3.22.1&#8243;][\/et_pb_divider][et_pb_text admin_label=&#8221;\u00c0 lire aussi&#8221; _builder_version=&#8221;3.22.1&#8243; z_index_tablet=&#8221;500&#8243; locked=&#8221;off&#8221;]<\/p>\n<h2><span class=\"st\">Projects in the same discipline<br \/><\/span><\/h2>\n<p>[\/et_pb_text][et_pb_blog posts_number=&#8221;4&#8243; include_categories=&#8221;35&#8243; show_author=&#8221;off&#8221; show_date=&#8221;off&#8221; show_pagination=&#8221;off&#8221; module_id=&#8221;page_type_blog&#8221; _builder_version=&#8221;3.22.1&#8243; header_level=&#8221;h4&#8243; border_width_bottom_fullwidth=&#8221;1px&#8221; border_color_bottom_fullwidth=&#8221;rgba(51,51,51,0.18)&#8221; custom_padding=&#8221;||50px|&#8221; z_index_tablet=&#8221;500&#8243; locked=&#8221;off&#8221;][\/et_pb_blog][\/et_pb_column][\/et_pb_row][\/et_pb_section]<\/p>\n","protected":false},"excerpt":{"rendered":"<p>2021Masters Projects@Mathematics and Statistics +Computer Science+Mathematics\/Statistics+Engineering+Medicine\u00a0#data-driven computational study#mathematical modeling#glaucoma#enhanced data set\u00a0 Project SummaryIntraocular pressure (IOP) is the pressure created by the fluids within the eye. Elevated IOP is clinically referred to as ocular hypertension and it represents a major risk factor for irreversible vision loss, as in glaucoma. However, the establishment of optimal IOP levels&hellip; <a class=\"continue\" href=\"https:\/\/wordpress-test.app.u-pariscite.fr\/diip\/influence-of-blood-pressure-and-aqueous-humor-dynamics-on-the-response-to-glaucoma-medication-a-data-driven-computational-study\/\">Lire la suite<span> Influence of blood pressure and aqueous humor dynamics on the response to glaucoma medication: a data-driven computational study<\/span><\/a><\/p>\n","protected":false},"author":560,"featured_media":2263,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"","_et_gb_content_width":"","footnotes":""},"categories":[57,1,29,35],"tags":[],"class_list":["post-1583","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-57","category-diip","category-masters-internship","category-mathematics-statistics"],"_links":{"self":[{"href":"https:\/\/wordpress-test.app.u-pariscite.fr\/diip\/wp-json\/wp\/v2\/posts\/1583","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/wordpress-test.app.u-pariscite.fr\/diip\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/wordpress-test.app.u-pariscite.fr\/diip\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/wordpress-test.app.u-pariscite.fr\/diip\/wp-json\/wp\/v2\/users\/560"}],"replies":[{"embeddable":true,"href":"https:\/\/wordpress-test.app.u-pariscite.fr\/diip\/wp-json\/wp\/v2\/comments?post=1583"}],"version-history":[{"count":3,"href":"https:\/\/wordpress-test.app.u-pariscite.fr\/diip\/wp-json\/wp\/v2\/posts\/1583\/revisions"}],"predecessor-version":[{"id":2317,"href":"https:\/\/wordpress-test.app.u-pariscite.fr\/diip\/wp-json\/wp\/v2\/posts\/1583\/revisions\/2317"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/wordpress-test.app.u-pariscite.fr\/diip\/wp-json\/wp\/v2\/media\/2263"}],"wp:attachment":[{"href":"https:\/\/wordpress-test.app.u-pariscite.fr\/diip\/wp-json\/wp\/v2\/media?parent=1583"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/wordpress-test.app.u-pariscite.fr\/diip\/wp-json\/wp\/v2\/categories?post=1583"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/wordpress-test.app.u-pariscite.fr\/diip\/wp-json\/wp\/v2\/tags?post=1583"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}